If I were doing the job I'd take out the screen however there is nothing to stop you cutting fender wherever you like.
The screen is a doddle to remove and replace but if you don't feel up to the task you could always call one of those auto glass replacement firms that has a mobile service and then get them to re-fit it when you're done.
To remove the screen procede as follows. Start by locating the join covers (they are in the centre) in the chrome trim inserts there are two of them, with a scredriver carefully slide them over (it doesn't matter which way) to reveal a gap in the trim. With both gaps revealed carefully prise the trim out of the rubber, it will bend a little, just take your time and coax it out don't yank it .
Once the trim is out take a couple of broad flat screwdrivers and get in the car. The next step is to coax the rubber seal under the metal seam, don't use any form of lube as you'll make the rubber spring back. Start at one top corner and gently tuck the rubber under the seam working your way along the top. Sometimes the rubber will try to slip back, if it does get someone to help you, you tuck the rubber under and they take hold of that screw driver you do the next bit and then take out the first one while they hold the second etc . Do the top and a third of each vertical pillar and then It'll be loose enogh to lift out. It sounds tough but it isn't I removed my screen in less than 5mins.
Relacement is just as easy.
When you are ready to re-fit the screen you'll need a friend to help, what you do is with the rubber fitted to the screen take a length of strong cord, string or wire and feed it into the groove of the rubber seal (where the seam would be if the screen were fitted) it may help if you lay the screen down. The ends of the cord must be at the bottom of the screen and they must overlap by a foot or so sothat you can get hold of them.
Now place the screen against the apature with the bottom of the seal over the seam so that the seam is resting of the cord. Get the screen a snug as you can, your friend now needs to push (not too hard) against the screen while you pull one end of the cord from inside the car. As you pull the cord you will see that it pulls the rubber over the seam. Do a bit on either side before doing the top to ensure the pressure is even on both sides. Once the rubber seal is in you can re-fit the metal trims.
Like I said before it sounds tough but it isn't 5 mins to remove and 10 (max) to re-fit.